COVID-19’s Body Self-Attack is Evident through Imaging

Recent radiology findings published in Skeletal Radiology by a Northwestern Medicine team pinpointed the causes of COVID-19 symptoms. CT, MRI, and ultrasound images unmask the virus’ pathways within the body and how it prompts the immune system to attack itself.


Sore muscles and achy joints are common symptoms of COVID-19 in some people. For others, the virus can spark otherwise dormant (or managed) rheumatoid arthritis, autoimmune myositis, or swollen and discolored toes, called “COVID toes.”


Corresponding author Swati Deshmukh, M.D., assistant professor of radiology at Northwestern University Feinburg School of Medicine, said, “We’ve realized that the COVID virus can trigger the body to attack itself in different ways, which may lead to rheumatological issues that require lifelong management. Many patients with COVID-related musculoskeletal disorders recover, but for some individuals, their symptoms become serious, impacting the quality of their life, which leads them to seek medical attention and imaging.”


Patients admitted to Northwestern Memorial Hospital between May 2020 and December 2020 were examined with CT, MRI, and ultrasound. Their results were analyzed and used to discover why certain people have lingering musculoskeletal symptoms post-COVID-19.


Edema, inflammatory changes in tissues, hematomas, and gangrene were all expressed in the patients; additionally, some images showed enlarged nerves which indicate injury or blood clots.


With these scans, radiologists can better direct patient care by steering them to a rheumatologist or dermatologist for further treatment. Radiologists could also suggest a COVID-19 diagnosis in patients who might have been unaware they had the virus. Overall, radiologists can use this information to improve patient outcomes. If a radiologist is familiar with the rheumatoid arthritis-prompting effects of COVID-19, they can send a patient with visible joint inflammation to a rheumatologist for further evaluation.


The study explores several types of musculoskeletal abnormalities, including visual samples of what radiologists should look for. Imaging providers should be alert and note the likelihood that pertinent findings are lurking in those images. This was (and is) not standard practice, because many radiologists were unsure what they were looking for. Now, with the results from this study, there is a clearer picture and understanding of the COVID-19’s progression.


RadParts is the world’s largest independent distributor of OEM replacement parts. We specialize in low-cost parts for repairing linear accelerator and radiation equipment. Our mission is to provide high-quality, user-friendly, low-cost parts and support for linear accelerators and radiation equipment. Contact RadParts at 877-704-3838 or visit us on the web: https://www.radparts.com.

Written by the digital marketing staff at Creative Programs & Systems: www.cpsmi.com.

Researchers Better Understand Sleep Patterns with MRI

Stages of deep sleep can significantly change our consciousness, just as it does in a coma or under anesthesia. Scientists have hypothesized that brain activity declines when we sleep, using research conducted with electroencephalography (EEG), a process that uses electrodes placed along a patient’s scalp to measure brain activity.

Anjali Tarun, a doctoral assistant at EPFL’s Medical Image Processing Laboratory within the School of Engineering, decided to investigate brain activity during sleep using magnetic resonance imaging (MRI.) Dimitri Van De Ville, lab lead, said, “MRI scans measure neural activity by providing important information in addition to EEGs.” Tarun used EEG to identify when study patients fell asleep, pinpointing the individual sleep stages. The MRI images were later used to produce spatial maps of neural activity, specifying brain states.

Deep sleep is reasonably challenging to achieve while undergoing an MRI, as the machines are quite noisy. Despite the hurdle, Tarun was able to leverage simultaneous MRI and EEG data from roughly thirty people. “Two hours is a relatively long time, meaning we were able to obtain a set of rare, reliable data,” she said. “MRIs carried out while a patient is performing a cognitive task usually last around 10 to 30 minutes.”

The data Tarun collected was surprising. “We calculated exactly how many times networks made up of different parts of the brain became active during each stage of sleep. We discovered that during light stages of sleep – that is, between when you fall asleep and when you enter a state of deep sleep – overall brain activity decreases. But communication among different parts of the brain becomes much more dynamic. We think that’s due to the instability of brain states during this phase.”

Van De Ville said, “What really surprised us in all of this was the resulting paradox. During the transition phase from light to deep sleep, local brain activity increased and mutual interaction decreased. This indicates the inability of brain networks to synchronize.”

Neural networks might be linked to our introspection process, memory, and spontaneous thoughts, all associated with consciousness. “We saw that the network between the anterior and posterior regions broke down, and this became increasingly pronounced with increasing sleep depth. A similar breakdown in neural networks was also observed in the cerebellum, which is typically associated with motor control.” At this point, the researchers aren’t sure why this happens; their findings are a novel step toward a better understanding of our sleep consciousness.

“Our findings show that consciousness is the result of interactions between different brain regions, and not in localized brain activity. By studying how our state of consciousness is altered during different stages of sleep, and what that means in terms of brain network activity, we can better understand and account for the wide range of brain functions that characterize us as human beings,” said Tarun.

For further reading, find the original article from EPFL.

RadParts is the world’s largest independent distributor of OEM replacement parts. We specialize in low-cost parts for repairing linear accelerator and radiation equipment. Our mission is to provide high-quality, user-friendly, low-cost parts and support for linear accelerators and radiation equipment. Contact RadParts at 877-704-3838 or visit us on the web: https://www.radparts.com.

Written by the digital marketing staff at Creative Programs & Systems: www.cpsmi.com.

MRI Providers: Watch for Patients with Metal Face Masks & Magnetic Eyelashes

Technologists are well-aware of the possibility of metal burns from MRI machines. Due to the components of an MRI, all metal must be removed prior to patients entering Zone III, the space before entering the scanner room. The COVID-19 pandemic has forced the world to wear face masks in public indoor areas, including medical procedures. Also, of recent fashion trends, women have become more prone to use magnetic eyelashes, a beauty product that is easier to apply and remove. Both have resulted in MRI patient injuries.


The U.S. Food and Drug Administration (FDA) released a statement warning health care providers that patients might be injured if they wear face masks with metal parts during a Magnetic Resonance Imaging (MRI) exam. These small metal parts are usually found within the nose area or throughout the mask fabric. Nose clips, wires, ultrafine particles, or antimicrobial coating (silver or copper) can become hot and burn MRI patients.


This note of caution comes as a patient received burns from donning a face mask during an MRI. “The FDA is reminding patients and providers that patients should not wear any metal during an MRI,” according to the statement issued.


The Journal of Applied Clinical Medical Physics issued a report explaining how magnetic eyelashes are unsafe in an MRI; some lashes can rapidly become moving projectiles. False eyelashes are placed onto magnetic eyeliner (applied to eyelids) or discreetly clamp around natural eyelashes. Patients might forget to mention the eyelashes and MRI technicians might not notice them.


All medical providers should screen patients for MRI safety. Tiny metallic objects within face masks or fake eyelashes can easily slide past an initial assessment. If patients experience burns while wearing face masks, providers are encouraged to report the incident to the FDA. Gathered reports help the FDA improve patient safety.
For more information regarding the FDA’s warning, read the full report. The complete journal article pertaining to magnetic eyelashes can be found here.


RadParts is the world’s largest independent distributor of OEM replacement parts. We specialize in low-cost parts for repairing linear accelerator and radiation equipment. Our mission is to provide high-quality, user-friendly, low-cost parts and support for linear accelerators and radiation equipment. Contact RadParts at 877-704-3838 or visit us on the web: https://www.radparts.com.


Written by the digital marketing staff at Creative Programs & Systems: www.cpsmi.com.

PET/MRI Outperforms PET/CT in Cancer Scanning

German researchers conducted a study in an effort to investigate the difference between combining Positron Emission Tomography (PET) with (MRI) Magnetic Resonance Imaging compared to PET with Computed Tomography (CT).


The scientists published their findings in the Journal of Nuclear Medicine, where they concluded that pairing (PET) with (MRI) is more effective at detecting lesions. This discovery yields a quicker, more effective use of centralized and whole-body staging in a single step. Moreover, it reduces the level of radiation exposure, making them ideal for younger patients.


PET/CT is typically the customary route in oncology imaging and staging due to its high sensitivity and resolution. However, PET/MRI offers higher soft-tissue distinction with lower radiation exposure. This combination has been prevalently dampened because there have not been enough significantly conclusive studies to exhibit both functionality and advantages.


The analysis was conducted by board-certified nuclear medicine physicians and radiologists who determined that PET/MRI made the process of discovering lesions and classifying them easier. Researchers noted that reduction in radiation exposure was perhaps the most significant advantage of PET/MRI over PT/CT.


Further studies are needed to improve the detection of nodules with PET/MRI; however, the scientists’ conclusions highlight the increasing potential of hybrid imaging with oncology diagnostics.


Read the entire study here. Looking to upgrade your linear accelerator or radiation equipment? The specialists at RadParts can answer your questions – contact us today.


RadParts is the world’s largest independent distributor of OEM replacement parts. We specialize in low-cost parts for repairing linear accelerator and radiation equipment. Our mission is to provide high-quality, user-friendly, low-cost parts and support for linear accelerators and radiation equipment. Contact RadParts at 877-704-3838 or visit us on the web: https://www.radparts.com.

AI-based MRI Interpretation Assistants from Siemens Healthineers Cleared by FDA

Two additional Siemens Healthineers Artificial Intelligence (AI)-based software assistants in the AI-Rad Companion family have been cleared by the Food and Drug Administration (FDA). During Magnetic Resonance Imaging (MRI), routine activities usually done by radiologists will now be completed by AI.


Brain segmentations, volume, and deviations are automatically marked by the AI-Rad Companion Brain MR for Morphometry Analysis. The AI-Rad Companion Prostate MR for Biopsy Support automatically segments the prostate. This process allows radiologists to mark lesions. In turn, prostate biopsies are targeted.


Peter Shen, Vice President of Innovation and Digital Business at Siemens Healthineers North America, said, “These new AI-Rad Companion applications for MR exams in the brain and prostate regions will help physicians manage their workloads and achieve a patient-focused decision-making process to increase efficiency and improve the quality of care.”


Various brain segments contain grey matter (nerve cells), white matter (nerve cell connections), and cerebrospinal fluid. The AI-Rad Companion Brain MR for Morphometry Analysis supports brain volumetry, which involves measuring the aforementioned segments. This process facilitates a comparison between normal volumes; any irregularities could be signs of Alzheimer’s Disease, Parkinson’s Disease, or dementia. Brain segmentation and comparison were typically performed manually or semi-manually before the new AI. Now, up to 30 brain segments can be read and then fed into a report where deviations from the norm are automatically marked.


Similarly, the AI-Rad Companion Prostate MR for Biopsy Support automatically segments and marks the prostate’s outer contour in seconds. Again, this process was typically done manually or semi-manually and could take several minutes. Radiologists can now read the report, mark suspect areas, and forward the results to urologists. The targeted, AI-supported biopsies can be precursors to cancer or other diseases.


Both software assistants are DICOM-compliant and can be used with many different MRI scanner brands, making integration effortless.


Check out this article for more information.


RadParts is the world’s largest independent distributors of OEM replacement parts. We specialize in low-cost parts for repairing linear accelerator and radiation equipment. Contact RadParts at 877-704-3838 http://www.radparts.com

Updates on the Radiation Markets with a Focus on LINAC

According to ResearchAndMarkets.com, a marketing research provider to businesses, the global radiation therapy market is expected to reach $10.11 billion in 2024, witnessing growth at CAGR of 3.38% over the period 2020-2024. Surging cancer cases, rising healthcare expenditure, economic and population growth with expanding urbanization are predicted to lead the global radiation therapy markets. However, a hindrance to these areas could be expected with stringent regulations and barriers to implementation. 

 

Advancements in technology, increasing preference towards non-invasive procedures, and public awareness, could be a few notable trends and are likely to develop over the next few years. The global radiation markets can be categorized into external beam radiation therapy, internal beam radiation therapy, and systemic radiotherapy. The external beam radiation therapy market is segregated both by type and device. 

 

Depending on the type, the global external beam market is segmented into the following categories: intensity-modulated radiation therapy (IMRT), image-guided radiation therapy (IGRT), tomotherapy, stereotactic radiosurgery, stereotactic body radiation therapy, and proton therapy. The global external beam radiation therapy market is also categorized into three areas – LINAC (Linear Accelerators), proton beam therapy devices, and compact advanced therapy devices. 

 

North America is the fastest-growing market because of the evolving usage in novel technologies, rising disposable income, and healthcare expenses. Rising awareness regarding procedures and sophisticated diagnostic approaches is a big part of the growth in this market. Europe comes in second for the largest market in radiation therapy and has already expanded into deeper economic levels. Radiation therapy treatment products and linear accelerator parts are expected to grow along with the trend in these developing market economies. 

 

For more information, read more at https://www.itnonline.com/content/radiation-therapy-market-update-focus-linac

Scientists Create a Particle Accelerator That Fits on a Chip

Scientists at Stanford and SLAC have created a silicon chip that can accelerate electrons by using an infrared laser to deliver a similar energy boost that takes microwaves many feet.

In a January issue of Science, a team led by an electrical engineer, Jelena Vuckovic, conveyed how he carved a nanoscale channel out of silicon, sealed it in a vacuum and sent electrons through an opening while beams of infrared light were transmitted by the channel walls to speed the electrons along.

The accelerator-on-a-chip demonstrated in Science is just a prototype. However, Vuckovic said its design and fabrication techniques could be scaled up to deliver particle beams accelerated enough to perform cutting-edge experiments in chemistry.

“The largest accelerators are like powerful telescopes. There are only a few in the world and scientists must come to places like SLAC to use them,” Vuckovic said. “We want to miniaturize accelerator technology in a way that makes it a more accessible research tool.”

“We can derive medical benefits from the miniaturization of accelerator technology in addition to the research applications,” Solgaard said.

Click here to read more about Vuckovic’s research on his discoveries regarding the silicon chip accelerator.

Radiotherapy Treatments for Bowel Cancer Patients to Be Shortened Due to COVID-19

An international panel of cancer experts has recommended a one-week treatment protocol for patients who need radiotherapy. On April 7, 2020, the group discussed the best way to minimize the additional issues that radiotherapy treatment causes, namely, weakened immune systems. Surgery, which usually happens one to two weeks after radiotherapy, can be safely delayed by up to 12 weeks, says the expert panel. 

 

People with bowel cancer are more susceptible to severe complications from COVID-19 because their immune systems are weakened. Shortening the length of radiotherapy replaces the need for chemotherapy, which typically can make the immune system even weaker. 

 

“The COVID-19 pandemic is a global emergency and we needed to work very quickly to identify changes that would benefit patients. Our recommendations were published 20 days after our first meeting. This process normally takes many months, if not years,” said David Sebag-Montefiore, professor of clinical oncology at the University of Leeds and who lead the panel of cancer experts. 

 

The panel, which was comprised of 15 top cancer professionals, showed that surgery could be safely postponed after radiotherapy from oncology equipment was performed. This protocol allows surgery to be scheduled after the peak of the pandemic. 

 

Read more on how radiation therapy has been affected by the COVID-19 pandemic here

PTW Announces Big News for the BEAMSCAN MR

The PTW has announced the 510(k) clearance from the U.S. Food and Drug Administration (FDA) for the BEAMSCAN MR Motorized 3D Water Phantom. The BEAMSCAN MR is now available on the market within the U.S. PTW has already completed the installation of the first item in North America located at the Princess Margaret Cancer Centre in Toronto, Ontario, Canada.

This new addition will provide a dedicated, fully equipped solution for beam data commissioning and annual QA of MR-LINACS. The center in Toronto is one of the largest cancer centers in the world. It is home to two state-of-the-art MR-LINAC systems, one being the Elekta Unity machine, which offers BEAMSCAN MR compatibility. To read more information about the BEAMSCAN MR and PTW, read this article here.